Board sweepers for 2HG

Both opposing boards arrive on the same turn

Damnation answers a board that two players built together. Teammates take one turn as a team, with one untap and one combat phase, so the opposing side commits two hands' worth of permanents in a single turn. That is what makes the timing here different from a duel.

The same arithmetic runs backwards once the wrath resolves. Both opponents rebuild from two hands on their next turn, so Supreme Verdict buys your team less time than it would in a duel. The compensation is sequencing: your partner can hold creatures back and redeploy after the sweeper resolves, inside the same turn.

One-sided and modal wraths gain the most

Ruinous Ultimatum destroys all nonland permanents your opponents control, and in 2HG “your opponents” is both of them. Seven mana clears two full boards and leaves your team's two standing. In a duel the same card answers one player.

Modal sweepers get a second job here: the mode you skip is the one your own team is standing on. Austere Command picks two of four effects, and Farewell picks one or more. Either can be aimed at what the other side actually has, rather than at everything on the table.

Selective wraths let your teammate keep a board

Fell the Mighty destroys every creature with power greater than target creature's power. Your range of influence covers your partner — so that target can be their smallest creature. Damning Verdict is selective in a different way. It spares every creature carrying a counter, on both sides of the table, so it rewards a counters deck rather than careful aim.

Two more count the board rather than clearing it. Decree of Pain draws a card for each creature destroyed, and Fumigate gains a life for each. Both are counting four players' creatures in 2HG where a duel would give them two.

A symmetrical wrath is a two-for-two

Wrath of God kills four players' creatures in 2HG, and two of those players are on your team. At a four-player Commander table it trades one board for three. Here it trades two for two, the ratio of a duel.

Living Death is the sharper case: every player exiles their creature cards and gets them back, so both opponents reanimate a graveyard on your sorcery. Kindred Dominance spares a single creature type — and your teammate is probably not playing it.

None of that makes a symmetrical wrath unplayable. Toxic Deluge is the standing exception: you choose X, so a small one clears two boards of utility creatures while your bigger threats survive. It also kills through indestructible, which “destroy all creatures” does not.